Abstract
Neuropsychiatric disturbances represent a common and uniquely challenging consequence
of stroke. These disorders arise at the intersection of lesion-related brain dysfunction
and psychological distress related to the event and its aftermath, making it difficult
to identify what symptom is a direct physiological consequence of the stroke. Depression,
anxiety, fatigue, apathy, emotionalism, and anger are the most common of these syndromes,
and posttraumatic stress disorder related to the stroke event has become increasingly
recognized as a relevant entity. Mania, obsessive–compulsive disorder, and psychosis
are less commonly encountered but potentially highly debilitating conditions that
may be underrecognized. Early identification and treatment may mitigate functional
impairment and improve quality of life. Evidence-based guidelines from the general
population are often relied upon to guide treatment. Further research is needed to
understand and tailor treatment of these disorders in the poststroke population.
Keywords
stroke - neuropsychiatry - poststroke depression - anxiety - posttraumatic stress
disorder - fatigue - apathy - emotionalism - anger - psychosis
